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Earliest human migrations and expansions of archaic and modern humans across continents began 2 million years ago with the migration out of Africa of Homo erectus.

This was followed by the migrations of other pre-modern humans including H.

Together, Crohn's disease and ulcerative colitis are frequently referred to as inflammatory bowel disease (IBD).Knowledge of early human migrations, a major topic of archeology, has been achieved by the study of human fossils, occasionally by stone-age artifacts and more recently has been assisted by archaeogenetics.Cultural and ethnic migrations are estimated by combining archaeogenetics and comparative linguistics.Key sites for this early migration out of Africa are Riwat in Pakistan (~2 Ma? heidelbergensis, the likely ancestor of both modern humans and Neanderthals, around 600,000 years ago. denisova (Denisovans) in Siberia (via archeological evidence) and East/South East Asia (via DNA evidence) is now well accepted.

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